Journal of Infection and Public Health
Volume 2, Issue 1 , Pages 41-46, 2009

Human papillomavirus infection is principally found with cervical intra-epithelial neoplasia-III in Toluca, State of Mexico

  • Hugo Mendieta-Zerón

      Affiliations

    • Faculty of Medicine, Autonomous University of the State of Mexico (UAEMex), Paseo Tollocan ESQ, Jesús Carranza, Col. La Moderna, CP. 50180, Toluca, State of Mexico, Mexico
    • Corresponding Author InformationCorresponding author. Present address: Felipe Villanueva sur 1209, Col. Rancho Dolores, CP. 50170, Toluca, México. Tel.: +52 722 2176605; fax: +52 722 2194122.
    • ,
  • Raúl de León-Escobedo

      Affiliations

    • Department of Pathology, General Regional Hospital 220, Instituto Mexicano del Seguro Social (IMSS), Paseo Tollocan No. 660, Col. Vértice, CP. 50150, Toluca, State of Mexico, Mexico
    • Present address: Universidad del Noreste, Tampico, Tamaulipas, Mexico; Prolongación Avenida Hidalgo 6315, Col. Nuevo Aeropuerto, CP. 89337, Tampico, Tamaulipas, México. Tel.: +52 833 2303830.

Received 17 September 2008; received in revised form 28 December 2008; accepted 12 January 2009.

Summary 

Introduction

To describe the prevalence of human papillomavirus infection (HPV) in cases of cervical intra-epithelial neoplasia (CIN), micro-invasive carcinoma and invasive carcinoma in Toluca, State of Mexico.

Materials and methods

Cross-sectional study analysing slides with the diagnosis of CIN I to invasive carcinoma for one year and reporting the presence of HPV; also identifying these cervical-uterine cancer stages noted during one semester in the registery of histopathological studies, at the Department of Pathology, General Regional Hospital 220, Instituto Mexicano del Seguro Social (IMSS).

Results

In one year, from a total of 5755 studies, 731 (13%) were of cervical-uterine cancer, 112 (16%) of these were positive for some stage of cervical cancer and 46.43% had HPV infection. In one semester, 2918 histopathological studies were done, 341 (11.68%) of these were cervix uterine biopsies, colposcopies and hysterectomies. 62 women (18.18%) diagnosed with CIN II–III, carcinoma in situ (CIS), micro-invasive carcinoma or invasive carcinoma and finding HPV infection in 51.92% of total cases.

Conclusions

The prevalence of HPV was higher than that reported in developed world and CIN II–III are the most common stages in Toluca, State of Mexico.

Keywords: Cervical intra-epithelial neoplasia, Cervical-uterine cancer, Detection, Human papillomavirus

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PII: S1876-0341(09)00003-3

doi:10.1016/j.jiph.2009.01.002

Journal of Infection and Public Health
Volume 2, Issue 1 , Pages 41-46, 2009

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