Journal of Infection and Public Health
Volume 2, Issue 1 , Pages 14-29 , 2009

The role of infections in the emergence of non-communicable diseases (NCDs): Compelling needs for novel strategies in the developing world

  • Dimie Ogoina

      Affiliations

    • Immunology Unit, Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), P.O. Box 06, Shika, Zaria, Kaduna State, Nigeria
    • These authors will serve as Guarantors of this review article.
    • ,
  • Geofrey C. Onyemelukwe

      Affiliations

    • Expert Committee on Non-Communicable Diseases in Nigeria, Immunology Unit, Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
    • These authors will serve as Guarantors of this review article.
    • Corresponding Author InformationCorresponding author. Tel.: +234 8037023974.

Received 14 December 2008 ,Revised 2 February 2009 ,Accepted 6 February 2009.

References 

  1. Facts on chronic disease: WHO Publication 2005. Retrieved August 2008. Available at www.who.int.
  2. Chronic diseases, facing the facts. WHO publication 2008. http://www.who.int/clip/chronic-disease-report/en/.
  3. Non-communicable diseases. Publication of Disease Control Priorities Project 2006. The World Bank. Available at www.worldbank.org.
  4. Surveillance of non-communicable diseases risk factors. WHO publication retrieved January 2008. www.who.int/mediacentre/factsheets/fs273/en/.
  5. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med. 2002;347(October 10 (15)):1175–1186
  6. Barker DJ. The development origin of adult disease. Am Coll Nutr. 2004;23(6):588–595
  7. Scott J. Homocysteine and cardiovascular disease. Q J Med. 1996;89:561–563
  8. Top 10 causes of Death. WHO Fact Sheet. March 2007. http://www.who.int/medicentre/factsheets/ts310.pdf.
  9. Barreto ML, Teixeira MG, Carmo HE. Infectious disease epidemiology. J Epidemiol Comm Health. 2006;60:192–195
  10. Daar AS, Singer PA, Persad DL, Pramming SK, Matthews DR, Beaglehole R, et al. Grand challenges in chronic non-communicable diseases. Nature. 2007;November (450):494–496
  11. Meador RJ. Acute rheumatic fever. E-medicine article updated October 22, 2007. Available at www.e-medicine.com.
  12. Bahn BJ, Appelt DM. Role of infection in Alzheimer's disease. J Am Osteopath Assoc. 2001;101(December (12 Suppl.)):1–6
  13. Dienstag JL, Isselbacher KJ. Tumours of the liver and biliary tract. In: 15th ed..  Braunwald F, et al. editor. Harrison's principles of internal medicine. vol. 91, no. 1:McGraw Hill (Pub.); 2001;p. 588–589
  14. Fakunle YM, Ajdukiewic AB, Greenwood B, Edington GM. Primary liver cell carcinoma (PLCC) in the northern Guinea savannah of Nigeria. Trans Roy Soc Trop Med Hyg. 1977;71(4):
  15. Bouman A, Heineman MJ, Faas MM. Sex hormones and the immune response in humans. Hum Rep Update. 2005;11(4):411–423
  16. Adrain Hill. The immunogentics of human infectious diseases. Annu Rev Immunol. 1998;16:593–617
  17. Bach Jean Francois . The effect of infectious in susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002;347(September (12)):911–920
  18. Richard R. Human papillomaviruses (HPV). In: 15th ed..  Braunwald F, et al. editor. Harrison's principles of internal medicine. vol. 1, no. 188:McGraw Hill (Pub.); 2001;p. 1118–1120
  19. Brady H, O’meara Y, Brenner B. The major glomerulopathies. In: 15th ed..  Braunwald F, et al. editor. Harrison's principle of internal medicine. vol. 1, no. 274:McGraw Hill (Pub.); 2001;p. 158
  20. Mohammed I. The role of immune complexes in human malaria and some of its complications. J Infect. 1982;4:97–104
  21. Barsoum R. Malarial Nephropathies. Nephrol Dial Transplant. 1998;13:1588–1597
  22. John Gever: Smoking conspires with viruses to advance COPD. MedpageToday, July 24, 2008. www.medpagetoday.com/pulmonary/smokingCOPD/ts/10249.
  23. Strachan DP. Hay fever, hygiene and household size. Br Med J. 1989;299:1259–1260
  24. Smith RS, Bloomfield S. The hygiene hypothesis and implications for home hygiene. Report of the international scientific forum on Home Hygiene, 2004.
  25. Greenwood BM, Voller A. Suppression of autoimmune disease in New Zealand Mice associated with infection with Malaria I & II. Clin. Exp. Immunol. 1970;8:793 and 805
  26. Epstein F. Atherosclerosis—an inflammatory disease. N Engl J Med. 1999;340(2):115–126
  27. Eder W, Ege M, Von-Mutius E. The asthma epidemic. N Engl J Med. 2006;355(November (21)):2226–2235
  28. Microbial Triggers of Chronic illness. Publication of American Academy of Microbiology 2005. www.asm.org.
  29. Strange Bed fellows; Infection and Chronic disease. Conference report. Canadian Public Health Association 2001. www.cpha.com.
  30. Connor SM, Taylor CE, Hughes S. Emerging infectious determinants of chronic diseases. Emerg Infect Dis. 2006;12(July (7)):1051–1057
  31. Pincus Seth. Potential role of infectious in chronic inflammatory diseases. vol. 71, no. 1. ASM Press; 2006;p. 529–535
  32. Scarisbrick A, Rodriguez M. Hit-Hit and Hit run. Viruses in the playing field of multiple sclerosis. Curr Neuro Neurosci Rep. 2003;3(June (3)):265–271
  33. Noseworthy J, Lucchiretti C, Rodriguez M, Weinsheinker B. Multiple Sclerosis. N Engl J Med. 2000;(September 28):938–952
  34. Sanjay Sethi . Bacterial Infections and the pathogenesis of COPD. Chest. 2000;117:2865–2913
  35. Hemalatha V, Srikanth P, Mallika M. Superantigens—concepts, clinical disease and therapy. Int J Med Microbiol. 2004;22(4):204–211
  36. Platts-Mill T, Male D, Hay F, Britton W, Westwood O. Hypersensitivity reactions. In:  Ivam R,  Brostoff J,  Male D editor. Immunology. 6th ed.. Mosby (Pub.); 2001;p. 323–382
  37. Lori A, Inman RD. Molecular mimicry and autoimmunity. N Engl J Med. 1999;(December):2068–2074
  38. Autoimmunity and autoimmune disease. In:  Ivam R,  Brostoff J,  Male D editor. Immunology. 6th ed.. Mosby (Pub.); 2001;p. 401–415
  39. Hypersensitivity. In Wikipedia Free encyclopedia updated 31 July 2008. Available at www.wikipedia.com.
  40. Carty SM, Snowden N, Silman AJ. Should infection still be considered as the most likely triggering factor for rheumatoid arthritis?. Ann Rheum Dis. 2004;63(Suppl. 11):i46–ii49
  41. Cancer. WHO Fact Sheet. 2006, Feb. Available at www.who.int.
  42. Cancer. In Wikipedia free encyclopedia. 2008 January. Available at www.wikipedia.com.
  43. Kim C, Koke K, Saito L, Miyamura T, Jay G. HBX gene of hepatitis B virus induces liver cancer in transgenic mice. Nature. 1991;351(May 23):317–320
  44. Brechot C. Pathogenesis of hepatitis B virus related hepatocellular carcinoma; old and new paradigms. Gastroenterology. 2003;127(5):556–561
  45. Gravitt P. HPV: the ultimate cancer initiator. HPV Today Monogr. 2003;3(September):1–4
  46. Yasunagu J, Matsuoka M. Human T-cell leukemia virus, type 1 induces adult T cell leukemia: from clinical aspects to molecular mechanism. Cancer Control. 2007;14(April (2)):133–140
  47. Cohen JI. Epstein-Barr virus infection. N Engl J Med. 2000;343(August 17 (7)):481–492
  48. Ming L, Thorgeirsson SS, Gail MH, Lu P, Harris CC, Wang N, et al. Dominant role of hepatitis B virus and cofactor role of aflatoxin in hepatocarcinogenesis in Qidong, China. Hepatology. 2002;36(November (5)):1046
  49. Ndububa DA, Yakicier CM, Ojo OS, Adeodu OO, Rotimi O, Ogunbiyi O, et al. P53 Codon 249 mutation in hepatocellular carcinoma from Nigeria. Afr J Med Med Sci. 2001;30(March–June (1–2)):125–127
  50. Onyemelukwe GC, Ogbadu G, Salifu A. Aflatoxins B1, B2, G1, G2 in primary liver cell carcinoma. Toxico Lett. 1982;10(February (2–3)):309–312
  51. Onyemelukwe GC, Nirodi C, West CE. Aflatoxin B in hepatocellular carcinoma. Trop Geogr Med. 1980;32(September (3)):237–240
  52. Khurana S, Dubey ML, Malla N. Association of parasitic infections and cancers. Indian J Med Microbiol. 2005;23(2):74–79
  53. Rezaee JA, Cunningham C, Davison A, Blackbourn DJ. Kaposi's sarcoma associated herpes virus immune modulation: an overview. J Gen Virol. 2006;87:1781–1804
  54. Lederman M. Immunopathogenesis of HIV; In HIV In-site Knowledge base. January 2006. Available at www.hivinsite.com.
  55. Beverley P. Tumour immunology. In:  Roit Ivan,  Brostof H,  Male D editor. Immunology. 6th ed.. Mosby (Pub.); 2001;p. 289–300
  56. Schouten JT. AIDS-Related Cancer; An update; In The Body, Retrieved August 2008, http://www/thebody.com/content/cert,4400.html.
  57. Whittle HC, Brown J, Marsh K, Blackman M, Jobe O, Shenton F. The effects of plasmodium Falciparum on immune control of B lymphocytes in Gambian children. Clin Exp Immunol. 1990;80(May (2)):213–218
  58. Lubega J. T-helper 1 versus T-helper 2 lymphocyte immunodysregulation is the central factor in genesis of Burkitt's lymphoma; hypothesis. Infect Agents Cancer. 2007;2(10):2–10
  59. Forrester T. Historic and early life origins of hypertension in Africans. J Nutr. 2004;134:211–216
  60. Malaria in pregnancy. Roll back malaria, WHO Retrieved August 2008. http://www.int/CMC-upload,10/000/015/369/RBMinfosheet_4.htm.
  61. Dogra SV. Intrauterine growth retardation. Update. Dec. 28, 2006. e-medicine, available at www.emedicine.com.
  62. Intrauterine growth retardation in newborn children. WHO publication. http://www/who.int/ceh/indication/ugrnewborn.pdf. Retrieved August 2008.
  63. Brown AS. Prenatal Infections as a risk factor for schizophrenia. Schizophrenia Bull. 2006;32(2):200–202
  64. Falase AO, Sekoni GA, Adenle AD. Dilated cardiomyopathy in young Africans; a sequel to infections. Afr J Med Med Sci. 1982;11:1–5
  65. Falase AO. Infections dilated cardiomyopathy in Nigeria. Heart Vessels Suppl. 1985;1:40–44
  66. Cook PJ, Lip GY. Infectious agents and atherosclerotic vascular disease. Q J Med. 1996;89:727–735
  67. Cook PJ, Lip GY, Davies P, Beevers DG, Wise R, Honeybourne D. Chlamydia pneumonia antibodies in severe essential hypertension. Hypertension. 1998;31:589–594
  68. Wimmer ML, Sandmann-Strupp R, Saikku P, Haberl RL. Association of Chlamydia Infection with Cardiovascular disease. Stroke. 1996;27(December (12)):2207–2210
  69. Falase AO. Peripartum heart disease. Heart Vessels Suppl. 1985;1:232–235
  70. Cenac C, Djibo A, Sueur JM, Chaigneau C, Orfila J. Chlamydia infection and Peripartum Cardiomyopathy. Nigerian Med Trops (Mars). 2000;60(2):137–140
  71. Bhakta P, Biswas B, Barnerjee B. Peripartum Cardiomyopathy. Yonsei Med J. 2007;48(5):731–747
  72. Ford l, Abdullahi A, Anjorin F, Danbauchi S, Isa M, Mauda G, et al. The outcome of peripartum cardiac failure in zaria. Nigeria Q J Med. 1998;91:93–103
  73. Wynne J, Braunwald E. The Cardiomyopathies and Myocarditis. In: 15th ed..  Braunwald Fauci, et al. editor. Harisson's principles of internal medicine. vol. 238:McGraw Hill (Pub.); 2001;p. 1359–1365
  74. Jaiyesimi F. Controversies and advances in Endomyocardial fibrosis—a review. Afr J Med Med Sci. 1982;11:37–46
  75. Andy JJ. Aetiology of Endomyocardial fibrosis (EMF). West Afr J Med. 2001;20(July–September (3)):199–207
  76. Andy JJ, Ogunowo PO, Akpan NA, Odigwe CO, Ekanem IA, Esin RA. Helminth associated hypereosinophilia and tropical endomyocardial fibrosis (EMF) in Nigeria. Acta Tropica. 1998;69(May (2)):127–140
  77. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311
  78. Gasbarrini A, Franceschi F, Armuzzi A, Ojetti V, Candelli M, Torre E, et al. Extradigestive manifestations of Helicobacter pylori gastric infection. Gut. 1999;45:9–12
  79. Paparello S, Hoffman S. Hyper-reactive malarial splenomegaly I & II. Postgrad Doct Afr. 1993;15(2–3):20–2448-51
  80. Bryceson A, Fakunle YM, Fleming AF, Crane G, Hutt MS, de Cock KM, et al. Malaria and splenomegaly. Trans Soc Trop Med Hyg. 1983;77:879–883
  81. Ramakrishna BS, Venkataraman S, Mukhopadhy GA. Tropical malabsorption. Postgrad Med J. 2006;82:779–787
  82. Fenollar F, Puechal X, Raoult D. Whipple's disease. N Engl J Med. 2007;356:55–66
  83. Water related diseases. WHO 2008. Available at www.who.int.
  84. Beisel WR. Infection induced malnutrition; from cholera to cytokines. Am J Clin Nutr. 1995;62:813–819
  85. Dhurandhar N. Infectoberity: obesity of infectious origin. J Nutr. 2001;131:2794–2797
  86. Prusiner SB. Novel Proteinaceous infectious particles cause Scrapie. Science. 1982;216:136–144
  87. Johnson RT, Gibbs CJ. Creutzfeldt–Jakob disease and related transmissible Spongiform Encephalopathies. N Engl J Med. 1998;339(December 31 (27)):1994–2004
  88. The Emerging Role of Infection in Alzheimer, Disease IOS Press 2008, May 25. Science Daily. Retrieved August 9, 2008.
  89. Vitiello B, Vitkovic L. The links between infections and Psychiatric Diseases. Medscape Psychiatry & Mental Health e-Journal, 1997, 2 (2) Retrieved August 2008.
  90. Gessaini A, Francis H, Sonan T, Giordano C, Akani F, Piquemal M, et al. HTLV-1 and Tropical spastic paraparesis in Africa. Lancet. 1986;2(September 20 (8508)):698
  91. Cabre P, Smadja D, Cabie A, Newton CJ. HTLV-1 and HIV infection of the Central Nervous System in tropical areas. J Neurol Neurosurg Psychiatry. 2000;68:550–557
  92. Ali G, Rashid S, Kamli MA, Shah PA, Allaqaband GQ. Spectrum of neuropsychiatric complications in 791 cases of typhoid fever. Trop Med Int health. 1997;2(4):314–318
  93. Danbauchi SS. Malaria presenting with self limiting cerebellar syndrome. Nigerian J Med. 1995;4(1):18–20
  94. Garg RK, Kerak B, Misra S. Neurological manifestation of malaria: an update. Neurol India. 1999;47:85–91
  95. Poliomyelitis. WHO Fact sheet Update January 2008. Available at www.who.int.
  96. Wild poliovirus weekly update; publication of Global polio eradication initiative. 2008, Aug 6. http://www.polioeradication.org/casecount.asp.
  97. Leprosy. WHO fact sheet October 2005. Retrieved August 2008. Available at www.who.int.
  98. Kibukamusoke J.W. (ed.) Tropical Nephropathy Citforge Pty Ltd, G.P.O. Box 1291, Canberra City, ACT 2601, Australia, 1984.
  99. Akinkugbe OO. Tropical nephropathy: an overview. Afr J Med Med Sci. 1992;21(October (1)):3–7
  100. Gilles HN, Hendrichse RG. Nephrosis in Nigerian Children Role of Malaria and effect of antimalarial treatment. Br Med J. 1963;2:27
  101. Kibukamusoke JW, Hunt MR, Wilkes NE. The Nephrotic syndrome in Ugandan and its association with Quartan Malaraie. Q J Med. 1967;36:393
  102. Aikhonbare HA, Abdulrahman MB. Acute glomerulonephritis in Zaria, Nigeria. Nig. J. Pediatrics. 1984;11(2):59–62
  103. Abdurrahman MB. The role of infectious agents in the aetiology and pathogenesis of childhood nephritic syndrome in Africa. J Infect. 1984;8(March (2)):100–109
  104. Gencay JB, Ridiger J, Tamm M, Soler M, Perruchoud A, Roth M. Increased frequency of Chlamydia pneumonia antibodies in patients with asthma. Am J Respir Crit Care Med. 2001;163:1097–1100
  105. Wjst M, Boakye D. Asthma in Africa. PLOS Med. 2007;4(February (2)):e72;0203–0205
  106. Onyemelukwe GC, Shakib F, Saeed TK, Salloum ZA, Lawande RV, Obineche E. RAST—specific IgE in Nigerian asthmatic patients. Ann Allergy. 1986;56(February (2)):167–170
  107. Casell GH. Infectious causes of chronic inflammatory disease and cancer. Emerg Infect Dis. 1998;4(July–September (3)):
  108. Malaria. WHO fact sheet 2007, May, Retrieved August 2008. Available at www.who.int.
  109. Nagel RL, Roth EF. Malaria and red cell genetic defects. Blood. 1989;74:1213–1221
  110. Malaria and the sickle cell Hemoglobin Gene 2002. April. Available at www.sickle.bioh.harvard.edu/malariasickle.html.
  111. Adaptation by Natural selection; Sickle cell Hemoglobin and Malaria. http://www.as.ua.edu/ant/bindos/ant475/sicklecell/sicklecell.pdf. 2004.
  112. Usanga EA, Luzzatto L. Adaptation of plasmodium falciparum to glucose-6-phosphate dehydrogenase deficient host red cells by production of parasite encoded enzyme. Nature. 1985;313:793–795
  113. Kajander EO, Ciftcioglu N. Nanobacteria: an alternative mechanism for pathogenic intra- and extra cellular calcification and stone formation. Proc Natl Acad Sci USA. 1998;95(July):874–889
  114. Urbano P, Urbano F. Nanobacteria: facts or fancies. PLOS Pathogens. 2007;3(5):e55;0567-0570
  115. Nelson PN, Carnegie PR, Martin J, Ejtehadi D, Hooley P, Roden D, et al. Demystified-Human Endogenous Retroviruses. Mol Pathol. 2003;56(February (1)):11–18
  116. WHO fact sheet. Immunization against diseases of public health importance. March 2005. Available at www.who.int.
  117. Ekwempu CC. Infection Theory of Eclampsia Re-evaluated. Int J Gynaecol Obstect. 1980;18(4):300–302

PII: S1876-0341(09)00008-2

doi: 10.1016/j.jiph.2009.02.001

Journal of Infection and Public Health
Volume 2, Issue 1 , Pages 14-29 , 2009

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